T.M.P.S. Oral
Composition
Per ml. solution:
| Trimethoprim |
20 |
mg. |
| Sulphamethoxazole |
100 |
mg. |
Description
The combination of Trimetoprim and Sulphamethoxazole acts synergistic and in many cases bactericidal against a large number of Gram-positive and Gram-negative bacteria, e.g. some Staphylococci, Streptococci, E. coli, Klebsiella spp., Salmonella spp., Proteus mirabilis, Pasteurella spp., Enterobacter aerogenes, Haemophilus influenza and Corynebacterium spp.. There is hardly any activity against Pseudomonas aeruginosa, Proteus vulgaris and some other Staphylococci. After oral administration both components will be absorbed rapidly and almost completely from the gastro-intestinal tract.
Indications
Infections caused by micro-organisms susceptible to Trimethoprim and/or Sulphamethoxazole, like gastro-intestinal-, respiratory- or urogenital tract infections and general infections in calves, sheep, goats, pigs and poultry.
Contra-indications
Serious liver- and/or renal dysfunctions; hypersensitivity to Sulphonamides; use in laying birds; diseases with decreased urine production (Oliguria, Anuria) and in combination with Ionophore Coccidiostatics because of the increased toxic action.
Side-effects
Hypersensitivity reactions, cross-resistance to Sulphonamides. Administration during two weeks or more may increase the risk for blood dyscrasias, folic acid deficiency and/or crystalluria.
Incompatibility with other drugs or substances
Simultaneous administration with Para-Aminobenzoic Acid or its esters (Procaine, Tetracaine) or with Methenamine.
Dosage and administration
For oral administration, via drinking water.
| Calves, sheep, goats |
: |
5 ml. per 40 kg. bodyweight, once or twice a day, during 5 days. (the solution must be diluted with water 1:5). |
|
|
|
| Poultry and turkeys |
: |
1 litre per 500-1000 litres of drinking water, during 4-5 consecutive days. |
Medicated drinking water should be used within 24 hours.
Withdrawal period
Storage
Store in a dry, dark place between 8°C and 25°C.
Packing
250 ml. glass bottle. Bottles packed in single boxes (12 bottles per carton box).
1 litre PE-Pharma bottle (12 bottles per carton box).
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